Digital Pathology Cases http://cases.humpath.com/ nk> Pathology Cases with Virtual Slides (Digital slides) Provided by humpath.com. See also the Pathology Digital Slidebox en SPIP - www.spip.net Venous extension of a thyroid follicular carcinoma http://cases.humpath.com/spip.php?article431 nk> http://cases.humpath.com/spip.php?article431 2013-07-08T10:19:51Z text/html en <p>TNM staging<br class='autobr' /> Discussion<br class='autobr' /> Thyroid carcinoma usually presents as an asymptomatic thyroid nodule.<br class='autobr' /> Thyroid cancer may show microscopic vascular invasion; however, internal jugular vein tumor thrombus is a rare complication of thyroid cancer.<br class='autobr' /> Thyroid carcinomas with massive intralumen invasion of the great veins are extremely rare and reported to have poor prognosis.<br class='autobr' /> Thyroid carcinoma causing tumor thrombus in the great veins is a rare situation and has been reported to have poor prognosis. (...)</p> - <a href="http://cases.humpath.com/spip.php?rubrique48" rel="directory">Thyroid pathology</a> <div class='rss_texte'><p><strong>TNM staging</strong></p> <p><strong>Discussion</strong></p> <p>Thyroid carcinoma usually presents as an asymptomatic thyroid nodule.</p> <p>Thyroid cancer may show microscopic vascular invasion; however, internal jugular vein tumor thrombus is a rare complication of thyroid cancer.</p> <p>Thyroid carcinomas with massive intralumen invasion of the great veins are extremely rare and reported to have poor prognosis.</p> <p>Thyroid carcinoma causing tumor thrombus in the great veins is a rare situation and has been reported to have poor prognosis.</p> <p>It can cause sudden death due to pulmonary embolism, and the management requires exclusive care.</p> <p>Solitary internal jugular vein invasion of thyroid cancer has been occasionally reported, but tumor thrombi extending to the mediastinum great veins is extremely rare.</p> <p>In the past, cases receiving palliative management have been reported due to the difficulty of surgical approach resulting in poor outcome.</p> <p>In general, patients can eventually come down with symptoms of SVC syndrome, which would be critical.</p> <p>Surgical treatment is necessary in collaboration with head and neck surgeons and cardiothoracic surgeons.</p> <p>Thompson et al. reported the first case of follicular thyroid carcinoma with extended tumor thrombus in the mediastinum great veins that was operated successfully.</p> <p>Thrombectomy is the most effective surgical treatment if possible.</p> <p>In the English language literature, 11 cases of differentiated thyroid cancer invasion in the mediastinum great veins have been reported that were treated by thrombectomy.</p> <p>Most of the previously reported cases revealed angio-invasion into a single vein.</p> <p>Reconstruction of the vessels is necessary for cases with massive invasion and adhesion to the great veins.</p> <p>Cases utilizing expanded polytetrafluoroethylene grafts or autologous tissue6 for reconstruction of mediastinum great veins are reported.</p> <p>Appropriate preoperative vascular imaging is important whenever angio-invasion is suspected.</p> <p>Enhanced CT and ultrasonography is reported to be useful for detecting tumor thrombi of thyroid malignancies.</p> <p>Taib and Hisham described the importance of the positive ring sign, which is a rim of contrast around the tumor thrombus on enhanced CT examination.</p> <p>This sign indicates the possibility of removing the thrombus by thrombectomy (without reconstruction) and is useful in deciding the surgical strategy.</p> <p>Multimodality treatment is recommended including surgery, external beam radiotherapy (EBRT), and RI therapy for aggressive thyroid cancer with great vein involvement.</p> <p><strong>Links</strong></p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> Venous obstruction of thyroid malignancy origin: the Antoine Lacassagne Institute experience. Marcy PY et al. <a href="http://www.wjso.com/content/7/1/40" class='spip_url spip_out auto' rel='nofollow external'>http://www.wjso.com/content/7/1/40</a></p> <p><strong>References</strong></p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> Follicular carcinoma of the thyroid with massive invasion into the cervical and mediastinum great veins: our own experience and literature review. Nakashima T, Nakashima A, Murakami D, Toh S, Shiratsuchi H, Yasumatsu R, Tominaga R, Komune S. Laryngoscope. 2012 Dec;122(12):2855-7. doi:10.1002/lary.23690 . PMID: #22951943#</p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> Mishra A, Agarwal A, Agarwal G, Mishra SK. Internal jugular vein invasion by thyroid carcinoma. Eur J Surg 2001; 167: 64–67.</p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> Lalak NJ, Campbell PR. Infiltrating papillary carcinoma of the thyroid with macroscopic extension into the internal jugular vein. Otolaryngol Head Neck Surg 1997; 117: S228–S230.</p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> Wiseman O, Preston PG, Clarke JM. Presentation of thyroid carcinoma as a thrombosed external jugular vein, with intraluminal tumour thrombus in the great veins. Eur J Surg Oncol 2000; 26: 816–817.</p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> Kim RH, Mautner L, Henning J, Volpe R. An unusual case of thyroid carcinoma with direct extension to great veins, right heart, and pulmonary arteries. Can Med Assoc J 1966; 94: 238–243.</p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> Thompson NW, Brown J, Orringer M, Sisson J, Nishiyama R. Follicular carcinoma of the thyroid with massive angioinvasion: extension of tumor thrombus to the heart. Surgery 1978; 83: 451–457.</p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> Wada N, Masudo K, Hirakawa S, et al. Superior vena cava (SVC) reconstruction using autologous tissue in two cases of differentiated thyroid carcinoma presenting with SVC syndrome. World J Surg Oncol 2009; 7: 75.</p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> Motohashi S, Sekine Y, Iizasa T, Nakano K, Numata T, Fujisawa T. Thyroid cancer with massive invasion into the neck and mediastinal great veins. Jpn J Thorac Cardiovasc Surg 2005; 53: 55–57.</p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> Taib NA, Hisham AN. Follicular thyroid carcinoma with direct tumour extension into the great cervical veins and right atrium: is transcervical thrombectomy a safe option? Asian J Surg 2007; 30: 216–219.</p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> Kobayashi K, Hirokawa M, Yabuta T, et al. Tumor thrombus of thyroid malignancies in veins: importance of detection by ultrasonography. Thyroid 2011; 21: 527–531.</p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> Hyer SL, Dandekar P, Newbold K, et al. Thyroid cancer causing obstruction of the great veins in the neck. World J Surg Oncol 2008; 6: 36.</p></div> Néphroblastome - EHB http://cases.humpath.com/spip.php?article430 nk> http://cases.humpath.com/spip.php?article430 2013-05-24T13:18:41Z text/html en - <a href="http://cases.humpath.com/spip.php?rubrique6" rel="directory">Renal diseases</a> Hematopathology | Digital slides http://cases.humpath.com/spip.php?article429 nk> http://cases.humpath.com/spip.php?article429 2012-12-12T13:19:03Z text/html en <p>Lymphomas and lymphoid lesions<br class='autobr' /> HPC:272 : Hyperplasia of the erythroid lineage. Reactional aspect.<br class='autobr' /> HPC:276 : Bone marrow localization of a prostate adenocarcinoma. Metastasis.<br class='autobr' /> HPC:277 : Acute leukemia after essential thrombocytosis;<br class='autobr' /> HPC:278 : CD5+ small cell lymphoma in bone marrow.<br class='autobr' /> HPC:279 : Lymphoplasmocytic lymphoma in bone marrow.<br class='autobr' /> HPC:280 : Follicular lymphoma in bone marrow.<br class='autobr' /> HPC:281 : Hairy cell leukemia.<br class='autobr' /> HPC:282 : Atypical myeloma cells in bone marrow.<br class='autobr' /> HPC:283 : (...)</p> - <a href="http://cases.humpath.com/spip.php?rubrique60" rel="directory">Lists of cases</a> <div class='rss_texte'><p><strong>Lymphomas and lymphoid lesions</strong></p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article272" class='spip_out'>HPC:272</a> : Hyperplasia of the erythroid lineage. Reactional aspect. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article276" class='spip_out'>HPC:276</a> : Bone marrow localization of a prostate adenocarcinoma. Metastasis. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article277" class='spip_out'>HPC:277</a> : Acute leukemia after essential thrombocytosis; <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article278" class='spip_out'>HPC:278</a> : CD5+ small cell lymphoma in bone marrow. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article279" class='spip_out'>HPC:279</a> : Lymphoplasmocytic lymphoma in bone marrow. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article280" class='spip_out'>HPC:280</a> : Follicular lymphoma in bone marrow. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article281" class='spip_out'>HPC:281</a> : Hairy cell leukemia. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article282" class='spip_out'>HPC:282</a> : Atypical myeloma cells in bone marrow.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article283" class='spip_out'>HPC:283</a> : Primary myelofibrosis. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article284" class='spip_out'>HPC:284</a> : T-cell rich B-cell lymphoma in bone marrow. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article285" class='spip_out'>HPC:285</a> : Dysmegacaryopoiesis without myelofibrosis. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article286" class='spip_out'>HPC:286</a> : Mantle cell lymphoma.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article287" class='spip_out'>HPC:287</a> : Chronic lymphocytic leukemia.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article288" class='spip_out'>HPC:288</a> : Follicular lymphoma (lymph node).<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article289" class='spip_out'>HPC:289</a> : Rosaï-Dorfman disease. Sinusal histiocytosis with massive lymphadenopathy.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article290" class='spip_out'>HPC:290</a> : Rosaï-Dorfman disease. Sinusal histiocytosis with massive lymphadenopathy.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article291" class='spip_out'>HPC:291</a> : Lymph node in rheumatoid polyarthritis.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article292" class='spip_out'>HPC:292</a> : Mixed cellularity, classic Hodgkin lymphoma.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article293" class='spip_out'>HPC:293</a> : Nodal cat scratch disease.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article294" class='spip_out'>HPC:294</a> : Small B cell lymphoma. Non otherwise specified - NOS.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article295" class='spip_out'>HPC:295</a> : Nodal toxoplasmosis.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article296" class='spip_out'>HPC:296</a> : Colonic MALT lymphoma.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article297" class='spip_out'>HPC:297</a> : Gastric diffuse large B-cell lymphoma (Gastric DLBCL).<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article298" class='spip_out'>HPC:298</a> : Residual disease of digestive MALT lymphoma after treatment.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article299" class='spip_out'>HPC:299</a> : Marginal zone B-cell lymphoma of the spleen.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article300" class='spip_out'>HPC:300</a> : Normal spleen (Idiopathic thrombopenic purpura).<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article301" class='spip_out'>HPC:301</a> : Mantle cell lymphoma of the ocular conjunctiva.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article302" class='spip_out'>HPC:302</a> : Mediastinal-pulmonary diffuse large B-cell lymphoma (DLBCL), EBV-associated.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article303" class='spip_out'>HPC:303</a> : Pulmonary plasmocytic MALT lymphoma.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article304" class='spip_out'>HPC:304</a> : Gastric MALT lymphoma (Gastric marginal zone lymphoma).<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article305" class='spip_out'>HPC:305</a> : Diffuse large B-cell lymphoma of the tonsil (DLBCL of the tonsil).<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article306" class='spip_out'>HPC:306</a> : Thyroid MALT lymphoma with lymphocytic thyroiditis.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article307" class='spip_out'>HPC:307</a> : Parotidal diffuse large B cell lymphoma and MALT lymphoma.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article308" class='spip_out'>HPC:308</a> : EBV-associated infectious mononucleosis. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article309" class='spip_out'>HPC:309</a> : Accessory salivary gland in Sjögren syndrome. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article310" class='spip_out'>HPC:310</a> : Thyroid follicular lymphoma. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article311" class='spip_out'>HPC:311</a> : Follicular gastritis and active chronic gastritis, non-atrophical, Helicobacter pylori-associated. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article312" class='spip_out'>HPC:312</a> : Nodal localization of a MALT lymphoma. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article313" class='spip_out'>HPC:313</a> : Minimal residual disease after treated gastric MALT lymphoma. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article314" class='spip_out'>HPC:314</a> : Mammary diffuse large B cell lymphoma (Mammary DLBCL). <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article315" class='spip_out'>HPC:315</a> : Mammary MALT lymphoma. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article316" class='spip_out'>HPC:316</a> : EBV-associated nasal T/NK lymphoma.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article317" class='spip_out'>HPC:317</a> : Pulmonary MALT lymphoma.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article318" class='spip_out'>HPC:318</a> : Lymphocytic interstitial pneumonia (LIP).<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article319" class='spip_out'>HPC:319</a> : Gastric MALT lymphoma (Fundus).<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article320" class='spip_out'>HPC:320</a> : Undifferentiated carcinoma of the nasopharynx (Epstein-Barr virus associated).<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article321" class='spip_out'>HPC:321</a> : Diffuse large B-cell lymphoma of the tonsil (DLBCL of the tonsil).<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article322" class='spip_out'>HPC:322</a> : Parotidal follicular lymphoma.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article323" class='spip_out'>HPC:323</a> : Diffuse large B-cell lymphoma (DLBCL) of the thyroid gland. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article324" class='spip_out'>HPC:324</a> : Accessory salivary gland in Sjögren syndrome. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article325" class='spip_out'>HPC:325</a> : Intestinal T-cell lymphoma.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article326" class='spip_out'>HPC:326</a> : Intra-epithelial T-cell lymphoma.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article327" class='spip_out'>HPC:327</a> : Lymphocytic colitis. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article328" class='spip_out'>HPC:328</a> : Lymphocytic gastritis. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article329" class='spip_out'>HPC:329</a> : Diffuse large B cell lymphoma (DLBCL) of duodenal mucosa.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article330" class='spip_out'>HPC:330</a> : Rectal marginal zone B-cell lymphoma - Rectal MALT lymphoma.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article331" class='spip_out'>HPC:331</a> : Follicular lymphoma grade 1 in lymph node. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article332" class='spip_out'>HPC:332</a> : HIV-associated nodal follicular hyperplasia.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article333" class='spip_out'>HPC:333</a> : Nodal EBV-associated infectious mononucleosis.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article334" class='spip_out'>HPC:334</a> : Nodal plasmocytoma. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article335" class='spip_out'>HPC:335</a> : Plasmocytic Castleman disease (associated to Kaposi sarcoma). <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article336" class='spip_out'>HPC:336</a> : ALK- anaplastic large cell lymphoma. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article337" class='spip_out'>HPC:337</a> : Classic Hodgkin lymphoma, mixed cellularity. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article338" class='spip_out'>HPC:338</a> : Nodal Langerhans histiocytosis with tuberculoid granulomatous pattern. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article339" class='spip_out'>HPC:339</a> : Kikuchi necrotizing adenitis. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article340" class='spip_out'>HPC:340</a> : T-cell rich diffuse large B cell lymphoma (T-cell rich DLBCL). <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article341" class='spip_out'>HPC:341</a> : ALK+ Large cell anaplastic lymphoma of the lymph node.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article342" class='spip_out'>HPC:342</a> : Burkitt lymphoma. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article343" class='spip_out'>HPC:343</a> : Richter syndrome. Activation of a chronic lymphocytic leukemia.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article344" class='spip_out'>HPC:344</a> : T-cell lymphoblastic lymphoma.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article345" class='spip_out'>HPC:345</a> : Mantle cell lymphoma.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article346" class='spip_out'>HPC:346</a> : Chronic lymphocytic leukemia. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article347" class='spip_out'>HPC:347</a> : Pseudonodular lymphocytic lymphoma (chronic lymphocytic leukemia).<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article347" class='spip_out'>HPC:347</a> : Chronic lymphocytic leukemia in bone marrow. <br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article349" class='spip_out'>HPC:349</a> : Sclerosing diffuse large B cell lymphoma of the mediastinum.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article350" class='spip_out'>HPC:350</a> : Progressive transformation of germinal centers.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article351" class='spip_out'>HPC:351</a> : Classical Hodgkin lymphoma, scleronodular type.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article352" class='spip_out'>HPC:352</a> : Nodular lymphocyte predominant Hodgkin lymphoma.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article353" class='spip_out'>HPC:353</a> : Nodal mantle cell B-cell lymphoma.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article354" class='spip_out'>HPC:354</a> : Chronic lymphocytic lymphoma-like follicular lymphoma.<br /><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://cases.humpath.com/spip.php?article355" class='spip_out'>HPC:355</a> : Systemic non-Langerhans cell histiocytosis.</p></div> Lingual digestive duplication cyst http://cases.humpath.com/spip.php?article428 nk> http://cases.humpath.com/spip.php?article428 2012-04-05T16:01:50Z text/html en - <a href="http://cases.humpath.com/spip.php?rubrique49" rel="directory">Oral pathology</a> Bone-forming tumors http://cases.humpath.com/spip.php?article427 nk> http://cases.humpath.com/spip.php?article427 2012-03-02T09:40:31Z text/html en admin <p>Digital cases - Digital slides<br class='autobr' /> osteoid osteoma<br class='autobr' /> HPC:414 : Osteoid osteoma<br class='autobr' /> osteoblastoma<br class='autobr' /> HPC:79 : Osteoblastoma<br class='autobr' /> HPC:147 : Osteoblastoma<br class='autobr' /> osteosarcomas<br class='autobr' /> HPC:166 (HP:166) : osteoblastic osteosarcoma<br class='autobr' /> HPC:157 (HPC:157) : giant cell-rich osteoblastic osteosarcoma<br class='autobr' /> HPC:140 (HPC:140) : osteoblastic osteosarcoma<br class='autobr' /> HPC:127 (HPC:127) : osteoblastic osteosarcoma<br class='autobr' /> HPC:126 : pulmonary metastase of an osteosarcoma<br class='autobr' /> HPC:115 : chondroblastic osteosarcoma of the calcaneum<br class='autobr' /> UI:323 - (...)</p> - <a href="http://cases.humpath.com/spip.php?rubrique59" rel="directory">Seminars</a> <div class='rss_texte'><p><strong>Digital cases - Digital slides</strong></p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> osteoid osteoma</p> <ul class="spip"><li> <a href="http://cases.humpath.com/spip.php?article414" class='spip_out'>HPC:414</a> : Osteoid osteoma</li></ul> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> osteoblastoma</p> <ul class="spip"><li> <a href="http://cases.humpath.com/spip.php?article79" class='spip_out'>HPC:79</a> : Osteoblastoma</li><li> <a href="http://cases.humpath.com/spip.php?article147" class='spip_out'>HPC:147</a> : Osteoblastoma</li></ul> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> osteosarcomas</p> <ul class="spip"><li> <a href="http://cases.humpath.com/spip.php?article166" class='spip_out'>HPC:166</a> (HP:166) : osteoblastic osteosarcoma</li><li> <a href="http://cases.humpath.com/spip.php?article157" class='spip_out'>HPC:157</a> (HPC:157) : giant cell-rich osteoblastic osteosarcoma</li><li> <a href="http://cases.humpath.com/spip.php?article140" class='spip_out'>HPC:140</a> (HPC:140) : osteoblastic osteosarcoma </li><li> <a href="http://cases.humpath.com/spip.php?article127" class='spip_out'>HPC:127</a> (HPC:127) : osteoblastic osteosarcoma</li><li> <a href="http://cases.humpath.com/spip.php?article126" class='spip_out'>HPC:126</a> : pulmonary metastase of an osteosarcoma</li><li> <a href="http://cases.humpath.com/spip.php?article115" class='spip_out'>HPC:115</a> : chondroblastic osteosarcoma of the calcaneum</li><li> <a href="http://www.path.uiowa.edu/cgi-bin-pub/vs/fpx_gen.cgi?slide=323&viewer=java&lay=iowa" class='spip_out' rel='external'>UI:323</a> - Osteosarcoma 1 (NOS)</li><li> <a href="http://www.path.uiowa.edu/cgi-bin-pub/vs/fpx_gen.cgi?slide=856&viewer=java&lay=iowa" class='spip_out' rel='external'>UI:856</a> - Osteosarcoma 2 (NOS)</li></ul> <p><strong>See also</strong></p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://www.humpath.com/spip.php?article5122" class='spip_out' rel='external'>HP:5122</a></p></div> Rectal mucosa prolapsus http://cases.humpath.com/spip.php?article426 nk> http://cases.humpath.com/spip.php?article426 2012-02-29T11:52:16Z text/html en admin <p>Digital slide<br class='autobr' /> NCK8-10 (ICSFramework)<br class='autobr' /> Test</p> - <a href="http://cases.humpath.com/spip.php?rubrique55" rel="directory">Rectum</a> <div class='rss_texte'><p><strong>Digital slide</strong></p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://app.parisdescartes.fr/cgi-bin/WebObjects/TRIBVNClientWS.woa/wa/lectureflash?jeton=9994_8692_20120102_13h52&WfmlZoomifyRoi=/ts/18/9994_8692/p/0000270a/sw/00008692.ndpi.apr" class='spip_out' rel='external'>NCK8-10</a> (<a href="http://app.parisdescartes.fr/cgi-bin/WebObjects/TRIBVNClientWS.woa/wa/lectureICSFramework?jeton=9994_8692_20120102_13h52&Number=1378&Agency=9993" class='spip_out' rel='external'>ICSFramework</a>)</p> <p>Test</p></div> EBV-associated salivary lymphoepithelial carcinoma http://cases.humpath.com/spip.php?article425 nk> http://cases.humpath.com/spip.php?article425 2012-02-29T09:33:35Z text/html en admin <p>Digital slides<br class='autobr' /> Epstein-Barr virus EBER probe : NCK8-9 (ICSFramework)</p> - <a href="http://cases.humpath.com/spip.php?rubrique58" rel="directory">Salivary glands</a> <div class='rss_texte'><p><strong>Digital slides</strong></p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> Epstein-Barr virus EBER probe : <a href="http://app.parisdescartes.fr/cgi-bin/WebObjects/TRIBVNClientWS.woa/wa/lectureflash?jeton=9994_9112_20120102_14h34&WfmlZoomifyRoi=/ts/18/9994_9112_201201021434/p/0000270a/sw/00009112.ndpi.apr" class='spip_out' rel='external'>NCK8-9</a> (<a href="http://app.parisdescartes.fr/cgi-bin/WebObjects/TRIBVNClientWS.woa/wa/lectureICSFramework?jeton=9994_9112_20120102_14h34&Number=1380&Agency=9993" class='spip_out' rel='external'>ICSFramework</a>)</p></div> prendre http://cases.humpath.com/spip.php?article424 nk> http://cases.humpath.com/spip.php?article424 2012-02-29T09:11:36Z text/html en admin - <a href="http://cases.humpath.com/spip.php?rubrique20" rel="directory">Dermatopathology</a> Small complex vascular malformation http://cases.humpath.com/spip.php?article423 nk> http://cases.humpath.com/spip.php?article423 2012-02-28T16:51:44Z text/html en admin <p>Slide 1<br class='autobr' /> H&E : NCK8-16 (ICSFramework)<br class='autobr' /> CD31 (endothelial marker) : NCK8-15 (ICSFramework)<br class='autobr' /> D2-40 (lymphatic marker) : NCK8-17 (ICSFramework)<br class='autobr' /> D2-40 (lymphatic marker) : NCK8-18 (ICSFramework)<br class='autobr' /> Slide 2<br class='autobr' /> H&E : NCK8-12 (ICSFramework)<br class='autobr' /> H&E : NCK8-14 (ICSFramework)<br class='autobr' /> D2-40 : [NCK8-13->http://app.parisdescartes.fr/cgi-bin/WebObjects/TRIB</p> - <a href="http://cases.humpath.com/spip.php?rubrique20" rel="directory">Dermatopathology</a> <div class='rss_texte'><p><strong>Slide 1</strong></p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> H&E : <a href="http://app.parisdescartes.fr/cgi-bin/WebObjects/TRIBVNClientWS.woa/wa/lectureflash?jeton=9994_8704_20120105_18h32&WfmlZoomifyRoi=/ts/18/9994_8704_201201051832/p/0000270a/sw/00008704.ndpi.apr" class='spip_out' rel='external'>NCK8-16</a> (<a href="http://app.parisdescartes.fr/cgi-bin/WebObjects/TRIBVNClientWS.woa/wa/lectureICSFramework?jeton=9994_8704_20120105_18h32&Number=1419&Agency=9993" class='spip_out' rel='external'>ICSFramework</a>)</p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> CD31 (endothelial marker) : <a href="http://app.parisdescartes.fr/cgi-bin/WebObjects/TRIBVNClientWS.woa/wa/lectureflash?jeton=9994_9176_20120105_18h29&WfmlZoomifyRoi=/ts/18/9994_9176_201201051829/p/0000270a/sw/00009176.ndpi.apr" class='spip_out' rel='external'>NCK8-15</a> (<a href="http://app.parisdescartes.fr/cgi-bin/WebObjects/TRIBVNClientWS.woa/wa/lectureICSFramework?jeton=9994_9176_20120105_18h29&Number=1418&Agency=9993" class='spip_out' rel='external'>ICSFramework</a>)</p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> D2-40 (lymphatic marker) : <a href="http://app.parisdescartes.fr/cgi-bin/WebObjects/TRIBVNClientWS.woa/wa/lectureflash?jeton=9994_9190_20120105_18h38&WfmlZoomifyRoi=/ts/18/9994_9190_201201051838/p/0000270a/sw/00009190.ndpi.apr" class='spip_out' rel='external'>NCK8-17</a> (<a href="http://app.parisdescartes.fr/cgi-bin/WebObjects/TRIBVNClientWS.woa/wa/lectureICSFramework?jeton=9994_9190_20120105_18h38&Number=1420&Agency=9993" class='spip_out' rel='external'>ICSFramework</a>)</p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> D2-40 (lymphatic marker) : <a href="http://app.parisdescartes.fr/cgi-bin/WebObjects/TRIBVNClientWS.woa/wa/lectureflash?jeton=9994_9194_20120105_18h40&WfmlZoomifyRoi=/ts/18/9994_9194_201201051840/p/0000270a/sw/00009194.ndpi.apr" class='spip_out' rel='external'>NCK8-18</a> (<a href="http://app.parisdescartes.fr/cgi-bin/WebObjects/TRIBVNClientWS.woa/wa/lectureICSFramework?jeton=9994_9194_20120105_18h40&Number=1421&Agency=9993" class='spip_out' rel='external'>ICSFramework</a>)</p> <p><strong>Slide 2</strong></p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> H&E : <a href="http://app.parisdescartes.fr/cgi-bin/WebObjects/TRIBVNClientWS.woa/wa/lectureflash?jeton=9994_9126_20120102_15h04&WfmlZoomifyRoi=/ts/18/9994_9126/p/0000270a/sw/00009126.ndpi.apr" class='spip_out' rel='external'>NCK8-12</a> (<a href="http://app.parisdescartes.fr/cgi-bin/WebObjects/TRIBVNClientWS.woa/wa/lectureICSFramework?jeton=9994_9126_20120102_15h04&Number=1384&Agency=9993" class='spip_out' rel='external'>ICSFramework</a>)</p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> H&E : <a href="http://app.parisdescartes.fr/cgi-bin/WebObjects/TRIBVNClientWS.woa/wa/lectureflash?jeton=9994_9120_20120102_14h51&WfmlZoomifyRoi=/ts/18/9994_9120/p/0000270a/sw/00009120.ndpi.apr" class='spip_out' rel='external'>NCK8-14</a> (<a href="http://app.parisdescartes.fr/cgi-bin/WebObjects/TRIBVNClientWS.woa/wa/lectureICSFramework?jeton=9994_9120_20120102_14h51&Number=1382&Agency=9993" class='spip_out' rel='external'>ICSFramework</a>)</p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> D2-40 : <a href="http://app.parisdescartes.fr/cgi-bin/WebObjects/TRIBVNClientWS.woa/wa/lectureflash?jeton=9994_9124_20120102_14h58&WfmlZoomifyRoi=/ts/18/9994_9124/p/0000270a/sw/00009124.ndpi.apr" class='spip_out' rel='external'>NCK8-13</a> (<a href="http://app.parisdescartes.fr/cgi-bin/WebObjects/TRIBVNClientWS.woa/wa/lectureICSFramework?jeton=9994_9124_20120102_14h58&Number=1383&Agency=9993" class='spip_out' rel='external'>ICSFramework</a>)</p></div> Congenital lobar hyperinflation (McLeod syndrome) http://cases.humpath.com/spip.php?article422 nk> http://cases.humpath.com/spip.php?article422 2012-02-28T16:20:32Z text/html en <p>Digital slides<br class='autobr' /> NCK8-19 (ICSFramework)</p> - <a href="http://cases.humpath.com/spip.php?rubrique12" rel="directory">Pulmonary diseases</a> <div class='rss_texte'><p><strong>Digital slides</strong></p> <p><img src="http://cases.humpath.com/local/cache-vignettes/L8xH11/puce-32883.gif" width='8' height='11' class='puce' alt="-" /> <a href="http://app.parisdescartes.fr/cgi-bin/WebObjects/TRIBVNClientWS.woa/wa/lectureflash?jeton=9994_9196_20120105_18h43&WfmlZoomifyRoi=/ts/18/9994_9196_201201051843/p/0000270a/sw/00009196.ndpi.apr" class='spip_out' rel='external'>NCK8-19</a> (<a href="http://app.parisdescartes.fr/cgi-bin/WebObjects/TRIBVNClientWS.woa/wa/lectureICSFramework?jeton=9994_9196_20120105_18h43&Number=1422&Agency=9993" class='spip_out' rel='external'>ICSFramework</a>)</p></div>